Research Program. Precision Nutrition and Cancer
Molecular Immunonutrition Group
Group leader: Dr. Moisés Laparra Llopis
Objectives: Immunonutritional-based precision intervention strategies to selectively modulate innate immune responses preventing/treating the risk for severity of diseases affecting the gut-liver axis.
Understanding of how tolerance and immunity regulate antitumoral responses, among other, this project aims at elucidating innate cell biology as a path forward to develop durable, long-lasting immune responses.
To defi ne the extent to which immunonutritional-based modulation can be translated into physiological benefits within the neuro-immunometabolic axis.
Dr. Moisés Laparra Llopis
Group leader of the Molecular Immunonutrition Group
José Moisés Laparra Llopis holds a PhD in Pharmacy gained during his stay at the High Research Council of the Spanish Government. His scientific career is focused on the field of intestinal homeostasis and the crosstalk within gut-liver axis. The novelty and scientific and social impact of his studies was used by the European Food Safety Authority to establish recommendations concerning staple foods. A continuous contact and interaction with internationally renowned research groups constitutes a constant in Dr. Laparra’s career. He held a leading position on prebiotic research awarded by The Fulbright Commission to conduct postdoctoral research in the Food Science Department at Cornell University.
Additionally, he participated in teaching activities that end up in a renowned honor thesis awarded by the professional organization for food science and technology professionals in the U.S. This experience favored his incorporation to the Institute of Translational Immunology at the University Medical Center of Mainz University as independent researcher. Dr. Laparra has published over 70 scientific articles and book chapters.
He has overseen several precompetitive public funded projects. As senior researcher at IMDEA Food he develops immunonutritional-based precision strategies to tumor suppressioner.
Phone: +34 91 727 81 00, ext. 213
Mario Fernández de Frutos
Mario Fernández de Frutos has a degree in Biology (2015) and a master´s degree in Cell Biology and Genetics (2016) both from the Universidad Autónoma de Madrid. During his degree and master´s research Project, he joined the group of Endocrine and Nervous System Pathophysiology at the Biomedical Research Institute “Alberto Sols” (IIb-CSIC), where he was responsible for the characterization of double knock out mice model for future studies of the Allan-Herndon-Dudley syndrome, a rare disease with serious neurologic alterations due to deficit of thyroid hormone transport during embryo development. He joined the Molecular Immunonutrition in Cancer group at IMDEA Food as a Ph candidate, focused on new precision therapeutic interventions based on molecular inmunonutrion to activate innate inmunity in the hepatocelular carcinoma.
Phone: +34 91 727 81 00
Adriana Quijada Freire
Adriana Quijada obtained her degree in Sanitary Biology at the University of Alcalá. She completed her Master’s degree on Immunology at the University Complutense de Madrid. In February of 2016, she joined the group of Antigenic Processing, at the National Centre for Microbiology (ISCIII), where she did her degree and master’s research projects. During this time, she carried out different research lines about viral immunology and antigenic processing and presentation. Here, she contributed to preliminary studies about in vivo monitoring of the human respiratory sincityal virus infection and the improving of techniques and procedures increasing the presentation of viral ligands on the surface of the cells and their detection with mass spectrometry. Currently, Adriana works in Dr. Moisés Laparra’s group of Molecular Immunonutrition at IMDEA Food focused immunonutritional strategies for a selective modulation of the neuro-immune axis and its impact in cognitive function.
Phone: +34 91 727 81 00
Laura Judith Marcos Zambrano
Dr. Laura Judith Marcos Zambrano obtained her BSc in Bioanalysis at the Central University of Venezuela (UCV). She has a master degree in Cellular Signalling, she obtained her Ph.D. at the Universidad Complutense de Madrid in 2017, her doctoral investigations were carried out in Hospital Gregorio Marañon (FIB-HGM), and her work was focused in the characterization of yeasts causing fungemia: identification of species and antifungal susceptibility, molecular epidemiology, and virulence factors. She has developed her scientific career in the field of molecular microbiology, mainly in lines related to the study of the epidemiology of fungal infections, molecular studies of resistance, antifungal susceptibility, biofilm formation, diagnostic improvements, pathogenicity, and molecular characterization of strains (genotyping). She has also worked in the invertebrate model of Galleria mellonella in a pre-doctoral stay at the Universitá degli Studi di Milano (Milan, Italy). She joined the inmunonutrition group at IMDEA Food in 2018, and her work is focused on the synergic relationship between the microbiota and the immune response triggered by different inmunonutrionital agents
Phone: +34 91 727 81 00
Dr. Bartosz Fotschki
Polish Academy of Sciences
Lorena Alejandra Lee Pellecer
Sandra Lozano Pacual
Laura Lorente Romeral
Nuria Zalckwar Diment
Lucía Martínez Carreras
|most relevant publications|
|main research grants|
Principal Investigator: Moisés Laparra Llopis
Principal Investigator: Mónica Haros
Principal Investigator: Lisardo Bosca Gomar (UCM)