Research Program. Precision Nutrition and Aging

Hepatic Regenerative Medicine Group

Group leader: Dr. Manuel Alejandro Fernandez Rojo

Objectives: The research conducted in the Hepatic Regenerative Medicine Group aims to provide non-invasive interventions to improve the treatment of chronic liver diseases and liver cancer by formulating novel diet-modifications. This includes nutritional approaches that promotes or represses therapeutic and deleterious proliferation of liver cells in cases of living-donor liver transplantation or after surgical removal of liver tumors, respectively. Our goal will be achieved using molecular, metabolism and cell biology examination on in vitro and in vivo experimental models of human liver diseases.

Dr. Manuel Alejandro Fernández Rojo

Group leader of the Hepatic Regenerative Medicine Group

Dr. Manuel Alejandro Fernández Rojo, native from Valladolid, Spain, received his B.S. in Biology from the University of Barcelona in 1999 and his PhD, from the same university, in 2005 by studying the role of Caveolin-1 on lipid metabolism and storage during liver regeneration within Dr. Albert Pol and Prof. Carlos Enrich’s group from the IDIBAPS Institute/School of Medicine (University of Barcelona). As a result of the outstanding quality of his research, the University of Barcelona awarded Dr. Fernández-Rojo with the Margalef Award. Moreover, the Science and Education Minister from the Spanish Government granted him the competitive Postdoctoral Fellowship to continue his research in liver physiology.

Hence, during the last 12 years, Dr. Fernández-Rojo continued his research in liver cell biology and metabolism in some of the most outstanding Australian research institutes. This includes eight years as postdoctoral fellow in Rob Parton’s group (The Institute for Molecular Bioscience, The University of Queensland), one year at the Monash Biomedicine Discovery Institute studying obesity and liver cancer and three years at the Hepatic Fibrosis Group from the QIMR Berghofer MRI understanding the role of hepatic stellate cells and liver progenitor cells on hepatic inflammation and chronic liver diseases.

In present, Dr. Manuel Alejandro Fernández Rojo is a “TALENTO Program” Fellow and in collaboration with Spanish, European and Australian eminent researchers, targets metabolic, cell biology and gene therapy-based strategies to improve the treatment of human chronic liver disorders.

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